epigenetic inhibitor library Search Results


epigenetic inhibitors library item no.11076  (Cayman Chemical)
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Cayman Chemical epigenetic inhibitors library item no.11076
Epigenetic Inhibitors Library Item No.11076, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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epigenetic chemical probe inhibitor library (cat. no. 17525)  (Cayman Chemical)
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Cayman Chemical epigenetic chemical probe inhibitor library (cat. no. 17525)
Epigenetic Chemical Probe Inhibitor Library (Cat. No. 17525), supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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epigenetic chemical probe inhibitor library (cat. no. 17525) - by Bioz Stars, 2026-02
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epigenetic inhibitor library  (Cayman Chemical)
90
Cayman Chemical epigenetic inhibitor library
Epigenetic Inhibitor Library, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/epigenetic inhibitor library/product/Cayman Chemical
Average 90 stars, based on 1 article reviews
epigenetic inhibitor library - by Bioz Stars, 2026-02
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hdac inhibitors from the cayman epigenetics screening library  (Cayman Chemical)
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Cayman Chemical hdac inhibitors from the cayman epigenetics screening library
<t>Pan-HDAC</t> inhibitor SAHA suppresses HAdV late gene expression. A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, 10 μM TSA, or 10 μM SAHA. (A) Cells were fixed at 24 hpi, and the RFP fluorescence intensities were quantified using the Cellomics HCS Platform. a.u., arbitrary units. Error bars represent the standard deviations (SD) of analytical replicates (n = 16). (B) Immunoblot analysis of cell lysates collected at 24 hpi confirmed the results in panel A. Both TSA and SAHA inhibited RFP production at 24 hpi. (C and D) A549 cells (C) and MRC-5 cells (D) were infected with Ad-late/RFP and treated with 10 μM SAHA. The expression of late proteins was analyzed by immunoblotting cell lysates collected at the indicated times. SAHA significantly reduces late gene expression in both cell lines.
Hdac Inhibitors From The Cayman Epigenetics Screening Library, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hdac inhibitors from the cayman epigenetics screening library/product/Cayman Chemical
Average 90 stars, based on 1 article reviews
hdac inhibitors from the cayman epigenetics screening library - by Bioz Stars, 2026-02
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epigenetic inhibitor library  (Cordis corporation)
90
Cordis corporation epigenetic inhibitor library
<t>Pan-HDAC</t> inhibitor SAHA suppresses HAdV late gene expression. A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, 10 μM TSA, or 10 μM SAHA. (A) Cells were fixed at 24 hpi, and the RFP fluorescence intensities were quantified using the Cellomics HCS Platform. a.u., arbitrary units. Error bars represent the standard deviations (SD) of analytical replicates (n = 16). (B) Immunoblot analysis of cell lysates collected at 24 hpi confirmed the results in panel A. Both TSA and SAHA inhibited RFP production at 24 hpi. (C and D) A549 cells (C) and MRC-5 cells (D) were infected with Ad-late/RFP and treated with 10 μM SAHA. The expression of late proteins was analyzed by immunoblotting cell lysates collected at the indicated times. SAHA significantly reduces late gene expression in both cell lines.
Epigenetic Inhibitor Library, supplied by Cordis corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/epigenetic inhibitor library/product/Cordis corporation
Average 90 stars, based on 1 article reviews
epigenetic inhibitor library - by Bioz Stars, 2026-02
90/100 stars
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epigenetic inhibitors library cayman chemical  (Cayman Chemical)
90
Cayman Chemical epigenetic inhibitors library cayman chemical
<t>Pan-HDAC</t> inhibitor SAHA suppresses HAdV late gene expression. A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, 10 μM TSA, or 10 μM SAHA. (A) Cells were fixed at 24 hpi, and the RFP fluorescence intensities were quantified using the Cellomics HCS Platform. a.u., arbitrary units. Error bars represent the standard deviations (SD) of analytical replicates (n = 16). (B) Immunoblot analysis of cell lysates collected at 24 hpi confirmed the results in panel A. Both TSA and SAHA inhibited RFP production at 24 hpi. (C and D) A549 cells (C) and MRC-5 cells (D) were infected with Ad-late/RFP and treated with 10 μM SAHA. The expression of late proteins was analyzed by immunoblotting cell lysates collected at the indicated times. SAHA significantly reduces late gene expression in both cell lines.
Epigenetic Inhibitors Library Cayman Chemical, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/epigenetic inhibitors library cayman chemical/product/Cayman Chemical
Average 90 stars, based on 1 article reviews
epigenetic inhibitors library cayman chemical - by Bioz Stars, 2026-02
90/100 stars
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Pan-HDAC inhibitor SAHA suppresses HAdV late gene expression. A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, 10 μM TSA, or 10 μM SAHA. (A) Cells were fixed at 24 hpi, and the RFP fluorescence intensities were quantified using the Cellomics HCS Platform. a.u., arbitrary units. Error bars represent the standard deviations (SD) of analytical replicates (n = 16). (B) Immunoblot analysis of cell lysates collected at 24 hpi confirmed the results in panel A. Both TSA and SAHA inhibited RFP production at 24 hpi. (C and D) A549 cells (C) and MRC-5 cells (D) were infected with Ad-late/RFP and treated with 10 μM SAHA. The expression of late proteins was analyzed by immunoblotting cell lysates collected at the indicated times. SAHA significantly reduces late gene expression in both cell lines.

Journal: Journal of Virology

Article Title: Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication

doi: 10.1128/JVI.00088-19

Figure Lengend Snippet: Pan-HDAC inhibitor SAHA suppresses HAdV late gene expression. A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, 10 μM TSA, or 10 μM SAHA. (A) Cells were fixed at 24 hpi, and the RFP fluorescence intensities were quantified using the Cellomics HCS Platform. a.u., arbitrary units. Error bars represent the standard deviations (SD) of analytical replicates (n = 16). (B) Immunoblot analysis of cell lysates collected at 24 hpi confirmed the results in panel A. Both TSA and SAHA inhibited RFP production at 24 hpi. (C and D) A549 cells (C) and MRC-5 cells (D) were infected with Ad-late/RFP and treated with 10 μM SAHA. The expression of late proteins was analyzed by immunoblotting cell lysates collected at the indicated times. SAHA significantly reduces late gene expression in both cell lines.

Article Snippet: HDAC inhibitors from the Cayman Epigenetics Screening Library that reduced RFP from Ad-late/RFP

Techniques: Gene Expression, Infection, Fluorescence, Western Blot, Expressing

HDAC inhibitors from the Cayman Epigenetics Screening Library that reduced RFP from Ad-late/RFP

Journal: Journal of Virology

Article Title: Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication

doi: 10.1128/JVI.00088-19

Figure Lengend Snippet: HDAC inhibitors from the Cayman Epigenetics Screening Library that reduced RFP from Ad-late/RFP

Article Snippet: HDAC inhibitors from the Cayman Epigenetics Screening Library that reduced RFP from Ad-late/RFP

Techniques:

HDAC2 activity is necessary for efficient expression of HAdV late genes. (A) A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, SAHA, MS-275, or MC1568 (10 μM each) for 24 h. Late gene expression decreased with MS-275 but not with MC1568. (B) A549 cells were transfected with 100 nM control, HDAC1, HDAC2, or HDAC3 siRNA for 48 h. (C) Cells knocked down for each HDAC were then infected with Ad-late/RFP (MOI of 10) for 24 h to analyze fiber and RFP protein expression. (D) co-IP was performed with IgG (negative control) or E1A antibody on cells infected and drug treated as in panel A. Input was 10% of the immunoprecipitation volume. HDAC2 knockdown decreased fiber and RFP expression, and the protein was found to interact with E1A.

Journal: Journal of Virology

Article Title: Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication

doi: 10.1128/JVI.00088-19

Figure Lengend Snippet: HDAC2 activity is necessary for efficient expression of HAdV late genes. (A) A549 cells were infected with Ad-late/RFP (MOI of 10) and treated with vehicle, SAHA, MS-275, or MC1568 (10 μM each) for 24 h. Late gene expression decreased with MS-275 but not with MC1568. (B) A549 cells were transfected with 100 nM control, HDAC1, HDAC2, or HDAC3 siRNA for 48 h. (C) Cells knocked down for each HDAC were then infected with Ad-late/RFP (MOI of 10) for 24 h to analyze fiber and RFP protein expression. (D) co-IP was performed with IgG (negative control) or E1A antibody on cells infected and drug treated as in panel A. Input was 10% of the immunoprecipitation volume. HDAC2 knockdown decreased fiber and RFP expression, and the protein was found to interact with E1A.

Article Snippet: HDAC inhibitors from the Cayman Epigenetics Screening Library that reduced RFP from Ad-late/RFP

Techniques: Activity Assay, Expressing, Infection, Gene Expression, Transfection, Control, Co-Immunoprecipitation Assay, Negative Control, Immunoprecipitation, Knockdown